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By analyzing data from polysomnograms (overnight recordings of sleep-related signals such as the EEG) we hope to develop ways to characterize EEG signals that will discriminate patients from normal subjects. We also want to develop analyses that identify changes in EEG signals that occur before an arousal (and may provide insights about the cause of the arousal). Study objectives: (1) to determine if the degree of irregularity (measured by Sample Entropy, SpEn) of an EEG signal varies systematically with sleep state (Wake, non-REM state 2, non-REM state 3/4, Rapid Eye Movement (REM) state); (2) to determine if an increase in SpEn of the EEG occurs prior to an arousal; (3) to determine whether SpEn of the EEG is different from normal in patients with sleep apnea. |
