Peter A. Crooks, Ph.D.
Department of Pharmaceutical Science
College of Pharmacy
University of Kentucky
907 Rose Street, 501A
Lexington, KY 40536
phone: 859-257-1718
fax: 859-257-7585
pcrooks@email.uky.edu
|
ABEER M. Al-GHANANEEM,
MSc, PhD in Medicinal Chemistry and Pharmaceutics
 
Dr. Al-Ghananeem research interests are in drug delivery and discovery with special focus in the area of nasal, sublingual, ophthalmic, and oral drug administration and disposition. Other areas of interest are improving systemic drug delivery via formulation and alteration of bio-pharmaceutical properties by designing prodrugs and codrugs.
Education:
-
Doctor of Philosophy; Medicinal Chemistry & Pharmaceutics; December 1999, University of Kentucky, USA
-
Master of Science; Medicinal Chemistry & Pharmaceutics, August 1999, University of Kentucky, USA
-
Bachelor of Science; Pharmacy; May 1993, Jordan University, Amman, Jordan
Riecords of Invention:
- "Intranasal Codeine for the Rapid Suppression of Cough"; Anwar Hussain, Lewis Dittert, and Abeer Al-Ghananeem, April 2000. US Patent Office, Registration # WO 0021515, US 98-104272 19981014.
- " Scopolamine Sublingual Spray for the Treatment of Motion Sickness". Provisional patent filed by UKRF on 2/25/2005
- "Sublingual Oxycodone for acute pain management". Provisional patent filed by UKRF on 3/28/2005
Publications:
- "Targeted Brain Delivery of 17- Estradiol via Nasally Administered Water Soluble
Prodrugs", Abeer Al-Ghananeem, Anwar Hussain, and Lewis Dittert. AAPS PharmSciTech 2002; 3(1).
- "Drug Targeting to the Lung: Chemical and Biological Consideration", Peter Crooks, Abeer Al-Ghananeem. Pharmaceutical Aerosol Technology (Drugs and the Pharmaceutical Sciences Series/134), Second edition. Anthony Hickey, Marcel Dekker, NY 200X 0097142232646. Sept 2003. ISBN: 0-8247-4253-2
- "Novel antiglaucoma prodrugs and codrugs of ethacrynic acid". Grazyna Cynkowska; Tadeusz Cynkowski, Abeer Al-Ghananeem, Hong Guo, Paul Ashton, and Peter A. Crooks. Bioorganic & Medicinal Chemistry Letters 2005; 15(15), 3524-3527
- "Evaluation of O3a-,O21-di-(N1-methyloxycarbonyl-2,4-dioxo-5-fluoropyrimidinyl)17a-hydroxy-5ß-pregnan-20-one as a novel potential antiangiogenic codrug". M. Howard-Sparks, A.M. Al-Ghananeem, A.P. Pearson and P.A. Crooks. J of Enzyme Inhibition and Medicinal Chemistry 2005;20(4)
- "Administration of oxycodone via sublingual spray for acute pain management". Abeer M. Al-Ghananeem, Ahmad H. Malkawi, and Peter A. Crooks. Pharmaceutical Research, In Press
- "Synthesis and Stability of Two Indomethacin prodrugs". Shyamala Chandrasekaran, Abeer Al-Ghananeem, and Peter A. Crooks. Bioorganic & Medicinal Chemistry Letters. In Press.
|