Genetics
BIO 304

Lecture: MWF, 10:00 am - 10:50, BS 116
Instructor: Dr. Charles Fox
Office: Ag Science Center North Room S-307B
Office Hours: Immediately after class or by appointment
E-mail: fox@uky.edu

TAs and their office hours
Tseten Yeshi, tgyesh2@uky.edu, 229-6312, F 2-4pm, BS 311
Travis Sexton, trsext2@uky.edu, 257-6271, F 2-3pm, BS 301

Tom Gawriluk, tgawriluk@uky.edu, 257-1807, W 3-4, THM 313

Text: Snustad and Simmons, Principles of Genetics, 4th Edition. Wiley, ISBN 0-471-69939-X.

Objective: The objective of this course is to introduce you the principles of transmission genetics, molecular genetics, and population genetics. You should come away from this course with a good understanding of basic principles and a good vocabulary of genetics terminology. Genetics is an exciting and very important field of biology; which is why this is a required course for many majors. But it can also be a lot of fun! My primary objective is to ensure that you learn basic genetics, but I also hope that you will enjoy this course and want to pursue further study in this field.

Reading Assignments: Readings in the textbook are listed on the syllabus. Although you might pass the class by skipping the reading assignments, you will not get a good grade. If you want to do well, read the assigned chapters! If you want to do really well, read the chapters before the class in which they will be discussed!

Course materials: The syllabus and other course materials, including all overheads used in lecture, will be presented on the web at http://www.uky.edu/~cfox/Courses/Genetics/. You are encouraged to download class overheads before each lecture so that you can write on them during class. You will not have time during class to copy the information presented on the overheads.

Attendance: I will not take attendance for lecture and will not deduct points from your grade for missing class. However, exams will be based on material presented in class. If you do not attend class, you will not do well on exams. In contrast, recitation sections are required and your TA may take attendance. Also, quizzes given during your recitation section will not be announced in advance, so you must attend your section to ensure you get credit for each quiz.

Exams and Grading:
Exams: (500 points) There will be five exams, one exam approximately every three weeks. Each exam will be worth 100 points and will cover only material from that section of the class.

Recitation sections: (100 points) There will be various quizzes and problem sets assigned during sections. Attendance at recitation sections is required. Quizzes will not be announced in advance, so you must attend recitation sections to ensure receiving credit for the quiz. Make-up quizzes will be given according to the exam make-up policy (see below).

Final grades will be based on the total points for the five exams plus recitation section.

Lecture exams: 500 points
Recitation sections: 100 points
Total: 600 points

Grades will then be awarded based on the following scale:

90 % or greater – A
80% to 89.9% – B
70% to 79.9% – C
60% to 69.9% – D
Less than 60 % – E

If final grades are lower than I consider appropriate, I might impose a curve that results in higher grades. I will not impose curves on individual exams, but may do so on the final grades in the class. However, I will not impose a curve that results in lower grades than students earn using the scale indicated above.

Missed Exams: Make-up exams or quizzes will be given only if an absence is pre-arranged (at least one week in advance) or if a valid excuse is provided (as per university regulations which are posted at www.uky.edu/Ombud/). An unexcused absence from an exam or quiz will result in a zero for that exam or quiz. There will be no exceptions to this rule. A missed exam or quiz will not be dropped from the final grade. Make-up exams will be given during my office hours immediately following your return. Note to student athletes: You must make arrangements at least one week in advance, with a note from the athletics department, if you will miss an exam or recitation section for a sporting event.

Cheating: I will not take attendance for lecture and will not deduct points from your grade for missing class. However, exams will be based on material presented in class. If you do not attend class, you will not do well on exams. In contrast, recitation sections are required and your TA may take attendance. Also, quizzes given during your recitation section will not be announced in advance, so you must attend your section to ensure you get credit for each quiz.

Overheads for Lectures in pdf format: (Important note: You may download most slides before class. However, I often modify my slides the night before class. Thus the attached slides are not always exactly the same slides used in class. Updated slides will be posted shortly after class).

Complete syllabus, lecture schedule and reading assignments
Transmission Genetics - 2, 3 or 6 slides per page
Short introduction to probability
Chromosomes part 1 - 2, 3 or 6 slides per page
Chromosomes part 2 - 2, 3 or 6 slides per page
Chromosomes part 3 - 2, 3 or 6 slides per page
Population Genetics Part 1 - 2, 3 or 6 slides per page
Population Genetics Part 2 - 2, 3 or 6 slides per page
Population Genetics Part 3 - 2, 3 or 6 slides per page
Quantitative Genetics - 2, 3 or 6 slides per page
Molecular Structure of Genes - 2, 3 or 6 slides per page
Molecular Structure of Chromosomes - 2, 3 or 6 slides per page
DNA Replication - 2, 3 or 6 slides per page
Transcription - 2, 3 or 6 slides per page
Translation - 2, 3 or 6 slides per page
Origins of Genetic Variation - 2, 3 or 6 slides per page
Genetics of Bacteria and Viruses Part 1 - 2, 3 or 6 slides per page
Genetics of Bacteria and Viruses Part 2 - 2, 3 or 6 slides per page
Techniques in Molecular Genetics - 2, 3 or 6 slides per page
Extranuclear Inheritance - 2, 3 or 6 slides per page
Regulation of Gene Expression Part 1 - 2, 3 or 6 slides per page
Regulation of Gene Expression Part 2 - 2, 3 or 6 slides per page
Developmental Genetics - 2, 3 or 6 slides per page

Review sheet for Exam 1
Review sheet for Exam 2
Review sheet for Exam 3
Review sheet for Exam 4
Review sheet for Exam 5

dnanim.gif (23379 bytes)

Other Useful resources on the web

Mendelian Genetics
    Mendelian genetic interactive crosses from North Harris College
    Mendelian genetic interactive crosses from Kansas State University
    Mendelian genetics problem sets from The Biology Project at the University of Arizona
    Punnet square tool from Oracle Thinkquest
    Virtual fly lab from Western Kentucky University
    Independent assortment animations from Sumanas, Inc.
    Linkage mapping game from Oracle Thinkquest
    Mendel web
    Cat coat color genetics from Cat Fanciers
    Interactive mouse genetics from Explore Learning

Cell-cycles
    Interactive cell models from Cells alive!
    Interactive cell cycle animation from Cells alive!
    Cell-cycle and mitosis tutorial from The Biology Project at the University of Arizona
    Phases of the cell cycle, illustrated using onion root tips, from The Biology Project at the University of Arizona
    Mitosis animation from Sumanas, Inc.
    Interactive mitosis animation from Cells alive!
    Meiosis tutorial from The Biology Project at the University of Arizona
    Meiosis animation from Sumanas, Inc.
    Interactive meiosis animation from Cells alive!
    Cytoskeleton tutorial from The Biology Project at the University of Arizona

Molecular Structure of Genes
    DNA workshop from PBS
    Structure of DNA animation from Sumanas, Inc.
    Meselson-Stahl experiment animations from Sumanas, Inc.
    Nucleic acids problem set from The Biology Project at the University of Arizona
    DNA structure from The Biology Project at the University of Arizona
    DNA from the beginning
    DNA replication animation from Wiley
    DNA replication animations from McGraw Hill

Transcription, Translation and the Genetic Code
    Translation Lab from Biology Labs On-Line at Cal State LA
    Eukaryotic Gene Expression problem set fromThe Biology Project at the University of Arizona
    Life cycle of an mRNA animation from Sumanas, Inc.
    mRNA splicing animation from Sumanas, Inc.
    Genetic code demonstration from Oracle Thinkquest
    Transcription and translation demonstration from the University of Utah
    Translation animation from Biostudio
    Translation animation from Brad Smith
    Polyribosomes animation from Sumanas, Inc.
    Life cycle of a protein animation from Sumanas, Inc.

Genome Projects
    Human genome project
    Map of the human genome
    TIGR microbial database - a listing of microbial genomes
    Flybase - a database for the Drosophila genome
    Dog genome project
    Maize genome database
    Caenorhabditis elegans genome

Bacterial Genetics
    Genetics of prokaryotes from The Biology Project at the University of Arizona
    Prokaryotes, Eukaryotes and Viruses tutorial from The Biology Project at the University of Arizona    

Viral Genetics
    HIV life cycle animation from Sumanas, Inc.

Regulation of Gene Expression
    Lac operon animation from Sumanas, Inc.
    Lac operon - Diagrams
    Lac operon - Diagrams
    Signal transduction from Wikipedia

Applications of Genetics
    Recombinant DNA Technology from The Biology Project at the University of Arizona
    Polymerase chain reaction animation from Sumanas, Inc.
    Polymerase chain reaction animation from Gene Almanac
    DNA chip technology animation from Sumanas, Inc.
    DNA sequencing animation from Wiley

Evolutionary History
    Tree of Life

General Sites
    Genetics glossary
    Genetics Virtual Library
    Talk of the Nation Science Friday with Ira Flatow (from NPR)
    Genetics and molecular biology research resources

If you find a link to be broken, please e-mail Dr. Fox at fox@uky.edu so I can fix the link or delete it.

Page last updated 18 August 2006 by Charles W. Fox (fox@uky.edu)